{"title":"White Jeans Method","description":"\u003cp\u003e\u003cmeta charset=\"UTF-8\"\u003e\u003cspan\u003eSupplements selected to support your six-week programme - targeted at the blood markers and metabolic pathways that matter most in perimenopause \u0026amp; menopause.\u003c\/span\u003e\u003c\/p\u003e","products":[{"product_id":"pure-melt-b12-folate","title":"Pure Melt B12 Folate","description":"\u003cp data-mce-fragment=\"1\"\u003eGreat-tasting, dissolving B12 folate vitamin lozenge.\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eAssists in cellular health, hormone and neurotransmitter production, and energy metabolism\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eUnique lozenge designed to dissolve in the mouth without requiring water\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSugar-free\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":40777955606713,"sku":"","price":48.0,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0591\/7438\/7897\/products\/PureEncapsulationsPureMeltB12Folate90LozFRONT.png?v=1629320280"},{"product_id":"ultramag-magnesium","title":"UltraMag Magnesium","description":"\u003cp data-mce-fragment=\"1\"\u003eEnhanced-absorption magnesium for bone health, muscle relaxation, and heart health.\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSupports healthy bone while promoting muscle relaxation and cardiovascular health\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eFosters numerous physiological functions, including nutrient metabolism and energy production\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":40777998729401,"sku":"","price":90.2,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0591\/7438\/7897\/products\/Pure-EncapsulationsUltramagMagnesium120CapFRONT.jpg?v=1629321202"},{"product_id":"vitamin-d3-liquid","title":"Vitamin D3 Liquid","description":"\u003cp data-mce-fragment=\"1\"\u003eSupport for bone, breast, prostate, cardiovascular, colon and immune health in easy-to-use liquid form\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSupports healthy bone composition\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003ePromotes cellular support for breast and prostate tissue\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSupports colon health by promoting healthy cellular function\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eConvenient liquid formula for easy dispensing\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":40778055024825,"sku":"","price":63.0,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0591\/7438\/7897\/products\/PureEncapsulationsVitaminD3LiquidFRONT.png?v=1629321982"},{"product_id":"organic-iron-plus","title":"Organic Iron Plus","description":"\u003cp data-mce-fragment=\"1\"\u003eBio-Practica Organic Iron Plus is a high strength and bio available form of iron with essential co-factors, vitamins and the herb Rosa canina.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eBio-Practica Organic Iron Plus may assist with:\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eMay assist in the management of dietary iron deficiency.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eContains nutrients involved in energy production.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eAssist red blood cells.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"BioPractica","offers":[{"title":"Default Title","offer_id":40787377324217,"sku":"","price":36.0,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0591\/7438\/7897\/products\/BioPracticaOrganicIronPlus30CapFRONT.jpg?v=1629419778"},{"product_id":"vitamin-d3-k2-drops","title":"Vitamin D3 + K2 Drops","description":"\u003cp data-mce-fragment=\"1\"\u003eVitamin D3 + K2 Drops by Seeking Health provides 12.5 mcg (500 IU) of D3 (as cholecalciferol) and 50 mcg of K2 (as menaquinone-4) in each drop. The cholecalciferol form of vitamin D3 used in this product is derived from cholesterol in sheep's wool, making it suitable for vegetarians.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e900 Servings.\u003c\/p\u003e","brand":"Seeking Health","offers":[{"title":"Default Title","offer_id":40788320714937,"sku":"","price":65.0,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0591\/7438\/7897\/products\/SeekingHealthVitaminD3_K2Drops900ServFRONT.jpg?v=1629429481"},{"product_id":"l-theanine","title":"L-Theanine","description":"\u003cmeta charset=\"UTF-8\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eL-Theanine is a naturally occurring, unique amino acid found in green tea leaves. L-theanine has been found to reduce stress by promoting relaxation without drowsiness, easing nervousness due to overwork and fatigue, and reducing nervous irritability. Human studies suggest that it may also be useful in supporting concentration and in reducing negative side effects from caffeine. \u003c\/span\u003e","brand":"Thorne","offers":[{"title":"Default Title","offer_id":42592802406585,"sku":"","price":88.5,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0591\/7438\/7897\/products\/XymogenL-TheanineFRONT.jpg?v=1658874289"},{"product_id":"omega-1250-fish-oil","title":"Omega 1250 (Fish Oil)","description":"\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eHi strength, ultra-pure Omega 3 fish oil\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSuperior fish oil oxidation parameters.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSourced from sustainably caught wild sardine and anchovy\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSupports nervous system and brain health\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSupports healthy cardiovascular system function\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eHelps in the maintenance of healthy blood lipids\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eRelieves inflammation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eConcentrated fish omega-3 triglycerides (Fish oils) contain eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). EPA and DHA are long-chain polyunsaturated essential fatty acids with a wealth of research regarding their impacts on overall health and targeted therapeutic benefits. Polyunsaturated fatty acids are comprised of two groups of essential fatty acids, omega-6’s (linoleic acid) and omega-3 (alpha-linolenic acid), with the latter, subsequently converting to eicosapentaenoic (EPA) and docosahexaenoic acid (DHA).\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThey are classified as essential because the rate of EPA and DHA biosynthesis from ALA is very low (8% and 1%, respectively); consequently, maintaining optimal endogenous levels to support physiological functional processes effectively requires regular intake from dietary sources. However, a broad body of evidence confirms that the intake of EPA and DHA across many sub-population groups in many Western countries is inadequate. This is a consequence of both inadequate omega-3 intake and excessive omega-6 consumption. EPA and DHA are also classified as essential because of the many important physiological functions they are involved in, including supporting heart health and brain and cardiovascular function.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cimg alt=\"\" src=\"https:\/\/designsforhealth.com.au\/wp-content\/uploads\/Screen-Shot-2022-03-18-at-2.34.11-pm.png\" data-mce-fragment=\"1\" data-mce-src=\"https:\/\/designsforhealth.com.au\/wp-content\/uploads\/Screen-Shot-2022-03-18-at-2.34.11-pm.png\"\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003ePharmacokinetics\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eOmega-3 polyunsaturated fatty acids (n-3 PUFA) are hydrolysed to monoglycerides and free fatty acids in the intestines. These by-products form part of micelles that are then absorbed via passive diffusion into the enterocytes.1,2 Free fatty acids are then involved in chylomicron formation. Chylomicrons enter the circulation and are distributed throughout tissue to be metabolised or stored. Metabolism of n-3 PUFAs can take place via several processes, including beta-oxidation, enzymatic biotransformation, as well as the production of lipid mediators. N-3 PUFAs are then incorporated into the phospholipid cell membrane where, upon stimulation, are released and converted to 20-carbon eicosanoids such as prostaglandins, prostacyclins and thromboxanes which go on to have some very influential biological effects in the immune and cardiovascular systems. N-3 PUFAs stored in this way in the brain contribute to the structure of the neuronal membrane and the myelin sheath. When not stored in cell membranes, dietary fats are stored in fatty tissues until they are oxidised and enter the Kreb’s cycle.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eMechanisms of Action\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eInflammation \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eEPA and DHA are responsible for the partial inhibition of multiple inflammatory processes, including the production of prostaglandins, leukotrienes and pro-inflammatory cytokines. EPA and DHA compete with arachidonic acid for the enzymes involved in producing pro-inflammatory mediators, inhibiting the inflammatory cascade. Cyclo-oxygenase-2 (COX-2) is responsible for stimulating prostaglandins at inflammatory sites. DHA specifically reduces COX-2 expression and activity, resulting in reduced inflammation.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003ePart of the anti-inflammatory action of EPA and DHA is due to its ability to inactivate pro-inflammatory transcription factor nuclear factor-kB. This action in turn, reduces the expression of pro-inflammatory genes, as well as the activation of anti-inflammatory transcription factor peroxisome proliferator-activated receptor gamma. N-3 PUFAs have the same effect as antioxidants by these same anti-inflammatory mechanisms, helping to prevent damage to endothelial cells and even cell death.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eEye Health\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eDHA is shown to have an integral role in maintaining the structure and function of the retina. DHA is a major structural element of the outer membrane of the retinal photoreceptor. High PUFA intake is shown to improve the response of the retinal cells to oxidative and inflammatory damage in animal studies.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNervous System\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eEPA and DHA are useful in supporting nervous system health and function via maintaining the nerve cell membranes. DHA is the most prevalent PUFA in the central nervous system and is required during brain and central nervous system development. Research has shown that a reduction in DHA can result in a reduced capacity to process sensory input.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThere is growing evidence that n-3 PUFAs protect against demyelination through their anti-inflammatory actions, including inhibition of microglia activation by inflammatory cytokines such as interferon-gamma (IFN-γ).\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eCardiovascular Function\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eA significant body of evidence has demonstrated an association between endogenous levels of EPA and DHA and cardiovascular health, which is attributed to a significant number of cardioprotective mechanisms of actions that omega-3 fatty acids are involved in. Such mechanisms include antioxidant, antiplatelet, promoting healthy blood lipid levels, cell membrane and vascular endothelial function, as well as reducing pro-inflammatory mediator concentrations (eicosanoids, prostaglandins, leukotrienes, and resolvins).\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThis has translated into clinically relevant outcomes, with findings from a broad body of evidence demonstrating a dose-dependent beneficial effect of omega-3 supplementation for improving cardiovascular health as measured by several clinical and biological endpoint subtypes.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eN-3 PUFAs can reduce endothelial dysfunction and arterial stiffness. Oxidative stress can induce endothelial dysfunction by reducing nitric oxide bioavailability – NO is essential for healthy vasodilation and has an anti-atherosclerotic action. It is thought that the positive effect of n-3 PUFAs on blood lipids is due to their ability to inhibit the production of very low-density lipoprotein (vLDL) in the liver\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eCognitive Function \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eDHA is highly prevalent in the brain. It is estimated that 20% of the brain's dry weight is comprised of PUFAs. Optimal levels are necessary for normal brain structure, function and health at all life stages. Specific mechanisms of omega-3 fatty acids that are involved in supporting healthy brain function include being a key cell membrane component, thus promoting optimal membrane fluidity, neurogenesis, intracellular signalling, synaptic transmission and repair processes, as well as inhibiting pro-inflammatory mediator-driven neuroinflammation.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eOmega-3 enhances neurotransmitter signalling and binding in the brain by improving membrane fluidity in the lipid bilayer. Furthermore, low DHA intake may impact neurotransmitter production in the brain, including acetylcholine, dopamine, serotonin, glutamate, norepinephrine and gamma-aminobutyric acid (GABA)\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eClinical evidence demonstrates a beneficial effect of omega-3 supplementation in young and middle-aged adults and older individuals. A comprehensive systematic review found that omega-3 supplementation improved endogenous fatty acid profiles, reading abilities (phonologic decoding time and visual analysis time) and enhanced neurocognitive function in young adults. Whilst other research into healthy ageing subjects notes that n-3 PUFAs may even help to slow cognitive decline. Improvements observed in middle-aged adults included enhanced memory functionality and brain structure (white matter microstructural integrity and grey matter volume), while omega-3 supplements protected against neurodegeneration in older individuals. Animal studies have shown that diets rich in n-3 PUFAs also maintain the integrity of the blood-brain barrier, which is associated with better cognitive function\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eVivo Mega\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eTwo vital factors to consider when ingesting therapeutic quantities of omega-3 fatty acids is purity and environmental impact. Extracted using urea technology, OmegAvail™ 1250 has superior oxidation parameters. It also has exceptional environmental parameters, being sustainably certified by IFFO Global Standard for Responsible for Supply and Friend of the Sea\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cimg alt=\"\" src=\"https:\/\/designsforhealth.com.au\/wp-content\/uploads\/Vivomega-fresh.png\" data-mce-fragment=\"1\" data-mce-src=\"https:\/\/designsforhealth.com.au\/wp-content\/uploads\/Vivomega-fresh.png\"\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eDirections to use:-\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eAdults: Take 1-2 capsules per day or as directed by your healthcare practitioner\u003c\/p\u003e","brand":"Designs for Health","offers":[{"title":"Default Title","offer_id":43921500504249,"sku":"","price":104.0,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0591\/7438\/7897\/files\/DFHOmega1250front.webp?v=1712870245"},{"product_id":"thyrosense","title":"Thyrosense","description":"\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cdiv title=\"Page 1\" class=\"page\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eThyroSense supports thyroid gland health and function and maintains healthy thyroid hormones. ThyroSense also supports metabolic rate and relieves fatigue. \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cspan\u003eThyroSense has been formulated to support functions influenced \u003c\/span\u003e\u003cspan\u003eby thyroid \u003c\/span\u003e\u003cspan\u003ehealth such as:\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eMetabolic rate and energy production. Healthy immune system function. Cognitive function.\u003cbr\u003ePeripheral blood circulation.\u003cbr\u003eHealthy digestion and liver health. \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eLow iodine formulation with dosage flexibility.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Vinka supplements","offers":[{"title":"Default Title","offer_id":45067130306745,"sku":"","price":76.5,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0591\/7438\/7897\/files\/Thyrosensefront.jpg?v=1750204909"},{"product_id":"berberine","title":"Berberine","description":"\u003cp\u003eOne of the most powerful natural compounds, berberine supports AMPK (adenosine monophosphate protein kinase) activation in the body — known as the ‘metabolic master switch’ — to help support blood sugar levels, blood pressure, healthy cholesterol levels and body composition. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNatroceutics Berberine Complex may support:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAMPK Activation\u003c\/li\u003e\n\u003cli\u003eWeight Management\u003c\/li\u003e\n\u003cli\u003eBlood Sugar Balance\u003c\/li\u003e\n\u003cli\u003eBalanced metabolism\u003c\/li\u003e\n\u003cli\u003eBalancing Gut Biome\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eKey features of Natroceutics Berberine Complex:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBerberine HCl + Liposomal berberine for enhanced bioavailability.\u003c\/li\u003e\n\u003cli\u003eIncreased active life and benefit.\u003c\/li\u003e\n\u003cli\u003eDual berberine actives, both rapid and sustained.\u003c\/li\u003e\n\u003cli\u003eOvercomes limitation of gut microbiome.\u003c\/li\u003e\n\u003cli\u003eEnhanced with liposomal chromium.\u003c\/li\u003e\n\u003cli\u003eConvenient to use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDirections for use:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAdults and children over 12 years: Take 1 capsule once or twice per day at the start of the largest meals of the day or as directed by your healthcare professional. Do not take on an empty stomach.\u003c\/p\u003e","brand":"NutraMedix","offers":[{"title":"Default Title","offer_id":47172406542521,"sku":null,"price":56.0,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0591\/7438\/7897\/files\/66612927ef0d8Natroceutics_BerberineFront_png.jpg?v=1778837834"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0591\/7438\/7897\/collections\/Vinka_WhiteJeans-3549_copy_Medium_4fff03d2-e385-45de-a87b-6e2abba50998.jpg?v=1779683087","url":"https:\/\/www.vinkasupplements.co.nz\/collections\/white-jeans-method.oembed","provider":"Vinka supplements","version":"1.0","type":"link"}